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Intervention reduces stress in parents of prematurely born children
Parents of children who are born preterm often experience high levels of stress. This can have negative effects on children’s socio-emotional and behavioural development. In a randomised controlled...
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Human-induced evolution in action
Salmon lice; (top) mature female with egg strings, (middle) mature female without egg stings, (bottom) immature louse. Image source: Wikimedia, Thomas Bjørkan Of the many characteristics humans...
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Open reading frame: cancer screening, aneurysm markers & syphilis prevention
Open Reading Frame brings together a selection of recent publication highlights from elsewhere in the open access ecosystem. This week we take a look at the past few weeks in medicine. Grip strength:...
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RNA polymerase III: it’s complex
Every first year biology student knows that three distinct RNA polymerase enzymes transcribe different types of genes. You might assume that these enzymes operate entirely independently of one another,...
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Open Reading Frame: new tarantulas, telomere tools & predicting evolution
Open Reading Frame brings together a selection of recent publication highlights from elsewhere in the open access ecosystem. This week we take a look at the past few weeks in biology. Imagine there’s...
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The safety and cardioprotective effects of phosphodiesterase type 5 inhibitors
Phosphodiesterase type 5 inhibitors (PDE5i), such as sildenafil, are currently prescribed for erectile dysfunction, however recent studies have suggested that they may also have beneficial cardiac...
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Open reading frame: brain training, cancer genomics & adolescent pregnancy
Open Reading Frame brings together a selection of recent publication highlights from elsewhere in the open access ecosystem. This week we take a look at the past few weeks in medicine. Depression...
View ArticlePest genomics: sequencing the house fly genome
The common house fly, Musca domestica L., is a sight most people associate with disease and decay. In a study in Genome Biology Jeffrey Scott from Cornell University, USA, sequenced the genome of this...
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Open Reading Frame: porpoise predators, spatial learning & necromancing...
Open Reading Frame brings together a selection of recent publication highlights from elsewhere in the open access ecosystem. This week we take a look at the past few weeks in biology. Solving a...
View ArticleBetter profiling for breast cancer: a role for E2F4?
Tumour profiling and the identification of genetic signatures provides new hope for more accurate predictions of outcomes in cancer. Current implementation of these methods in the clinic centre around...
View ArticleStressed vertebrates: the role of Otp regulation
Jawed vertebrates respond to stress at the physiological level and release hormones, such as cortisol, to help cope with the stimuli. Many aspects of this response are evolutionarily conserved across...
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Open reading frame: early signs of cancer, TB in pregnancy & adverse drug...
Open Reading Frame brings together a selection of recent publication highlights from elsewhere in the open access ecosystem. This week we take a look at the past few weeks in medicine. The burden of...
View ArticleInsights into the genetics of sociality from William’s syndrome
William’s syndrome (WS) is a rare chromosomal disorder where individuals typically have ‘elfin’ features, learning disabilities and cardiovascular problems. WS is often dubbed ‘the opposite of autism’,...
View ArticleHow sweet it is: sugar metabolism networks in peach
A delicious summer peach is valued for its taste, but what controls the balance of sugars and acids that combine to make the fruit so sweet? Although the production and accumulation of individual...
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Open Reading Frame: African genomes, sperm size & fish conservation
Open Reading Frame brings together a selection of recent publication highlights from elsewhere in the open access ecosystem. This week we take a look at the past few weeks in biology. African genomes...
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Route of administration of testosterone therapy affects cardiovascular risk
Testosterone replacement therapy (TRH) is increasing used by older men with low testosterone to improve muscle strength, exercise capacity, bone mineral density, libido and insulin sensitivity....
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Harnessing the immune system to treat cancer: melanoma to renal cell carcinoma
Immunotherapy for cancer, whereby the immune system is harnessed as a means to target and neutralise tumour cells, is heralded as a promising approach for the treatment of a range of cancers. The...
View ArticleUsing acetate to keep up with the metabolic of needs of cancer
Cancer cells grow and proliferate even under limiting nutrient conditions such as hypoxia. How cancer cells derive the cellular building blocks, such as fatty acids, and proliferate during hypoxic...
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Open Reading Frame: chemoprevention, TB detection & lung cancer prognosis
Open Reading Frame brings together a selection of recent publication highlights from elsewhere in the open access ecosystem. This week we take a look at the past few weeks in medicine. Increasing...
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Open Reading Frame: making memories, autism genetics & hair growth
Open Reading Frame brings together a selection of recent publication highlights from elsewhere in the open access ecosystem. This week we take a look at the past few weeks in biology. A memory of...
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